Abstract Introduction This study aimed to investigate the long-term prognostic effects of different alteplase doses on patients with acute ischemic stroke (AIS).Methods In this cohort study, we enrolled 501 patients with AIS treated with intravenous thrombolysis with alteplase, with the primary endpoint event of recurrence of ischemic stroke and th
Background: The initiator of cytokine storm in Coronavirus disease (COVID-19) is still unknown.We recently suggested a complex interaction of matrix metalloproteinases (MMPs), Fas ligand (FasL), and viral entry factors could be responsible for the cytokine outrage In COVID-19.We explored the molecular dynamics of FasL/MMP7-9 in COVID-19 conditions
This study identifies key challenges to measure the carbon footprint (CF) over the whole life cycle of buildings in Chile, although its findings are also applicable to other countries.This paper presents four of the said challenges that emerge from the analysis of certification programs, design guides, databases, CF/LCA calculators, standards, and
The active interaction of the foreland domain represented by the Adria Foreland Plate and the surrounding orogenic systems is discussed by taking a perspective from the Central-Northern Apennines.The present-day tectono-kinematic framework of the Adriatic and surrounding regions is considered with respect to structural setting of the Central-Northe